node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rfer_0460 | Rfer_0466 | Rfer_0460 | Rfer_0466 | Methionine synthase (B12-dependent). | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.998 |
Rfer_0460 | Rfer_1327 | Rfer_0460 | Rfer_1327 | Methionine synthase (B12-dependent). | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.923 |
Rfer_0460 | Rfer_1520 | Rfer_0460 | Rfer_1520 | Methionine synthase (B12-dependent). | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.836 |
Rfer_0460 | Rfer_2294 | Rfer_0460 | Rfer_2294 | Methionine synthase (B12-dependent). | Cystathionine beta-lyase. | 0.944 |
Rfer_0460 | Rfer_3160 | Rfer_0460 | Rfer_3160 | Methionine synthase (B12-dependent). | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.923 |
Rfer_0460 | Rfer_3460 | Rfer_0460 | Rfer_3460 | Methionine synthase (B12-dependent). | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.836 |
Rfer_0460 | ahcY | Rfer_0460 | Rfer_0652 | Methionine synthase (B12-dependent). | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.942 |
Rfer_0460 | metZ | Rfer_0460 | Rfer_2682 | Methionine synthase (B12-dependent). | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.944 |
Rfer_0466 | Rfer_0460 | Rfer_0466 | Rfer_0460 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent). | 0.998 |
Rfer_0466 | Rfer_1327 | Rfer_0466 | Rfer_1327 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.925 |
Rfer_0466 | Rfer_1520 | Rfer_0466 | Rfer_1520 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.829 |
Rfer_0466 | Rfer_2294 | Rfer_0466 | Rfer_2294 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase. | 0.926 |
Rfer_0466 | Rfer_3160 | Rfer_0466 | Rfer_3160 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.925 |
Rfer_0466 | Rfer_3460 | Rfer_0466 | Rfer_3460 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.829 |
Rfer_0466 | ahcY | Rfer_0466 | Rfer_0652 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.940 |
Rfer_0466 | metZ | Rfer_0466 | Rfer_2682 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.926 |
Rfer_0881 | Rfer_1520 | Rfer_0881 | Rfer_1520 | Aminotransferase. | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.911 |
Rfer_0881 | Rfer_2294 | Rfer_0881 | Rfer_2294 | Aminotransferase. | Cystathionine beta-lyase. | 0.923 |
Rfer_0881 | Rfer_2880 | Rfer_0881 | Rfer_2880 | Aminotransferase. | 3-mercaptopyruvate sulfurtransferase. | 0.905 |
Rfer_0881 | Rfer_3460 | Rfer_0881 | Rfer_3460 | Aminotransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.911 |