node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rfer_1314 | ftsQ | Rfer_1314 | Rfer_3422 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.942 |
Rfer_1314 | ftsW | Rfer_1314 | Rfer_3426 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Cell cycle protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.707 |
Rfer_1314 | mraY | Rfer_1314 | Rfer_3428 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.883 |
Rfer_1314 | murC | Rfer_1314 | Rfer_3424 | Cyanophycin synthetase; Belongs to the MurCDEF family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.867 |
Rfer_1314 | murD | Rfer_1314 | Rfer_3427 | Cyanophycin synthetase; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.944 |
Rfer_1314 | murF | Rfer_1314 | Rfer_3429 | Cyanophycin synthetase; Belongs to the MurCDEF family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.937 |
Rfer_1314 | murG | Rfer_1314 | Rfer_3425 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.942 |
Rfer_1314 | murI | Rfer_1314 | Rfer_2597 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.558 |
ddl | ftsQ | Rfer_3423 | Rfer_3422 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.986 |
ddl | ftsW | Rfer_3423 | Rfer_3426 | D-alanine--D-alanine ligase; Cell wall formation. | Cell cycle protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.880 |
ddl | mraY | Rfer_3423 | Rfer_3428 | D-alanine--D-alanine ligase; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.925 |
ddl | murC | Rfer_3423 | Rfer_3424 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
ddl | murD | Rfer_3423 | Rfer_3427 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.958 |
ddl | murE | Rfer_3423 | Rfer_3430 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.900 |
ddl | murF | Rfer_3423 | Rfer_3429 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.994 |
ddl | murG | Rfer_3423 | Rfer_3425 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.961 |
ddl | murI | Rfer_3423 | Rfer_2597 | D-alanine--D-alanine ligase; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.488 |
ftsQ | Rfer_1314 | Rfer_3422 | Rfer_1314 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cyanophycin synthetase; Belongs to the MurCDEF family. | 0.942 |
ftsQ | ddl | Rfer_3422 | Rfer_3423 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | D-alanine--D-alanine ligase; Cell wall formation. | 0.986 |
ftsQ | ftsW | Rfer_3422 | Rfer_3426 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell cycle protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.964 |